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  • When might non-puerperal induction of lactation be requested and what volumes of milk are realistic to expect?
  • Induction of lactation: taking a history and why each question matters
  • NDC Clinical Guidelines Induction of Lactation Part 1. The most reliable element in non-puerperal induction of lactation protocols is stimulation of the breasts and nipples + frequent flexible milk removal
  • NDC Clinical Guidelines Induction of Lactation Part 2. Do hormonal medications improve breastmilk volumes in non-puerperal induction of lactation?
  • NDC Clinical Guidelines Induction of Lactation Part 3. Does domperidone improve breastmilk volumes in non-puerperal induction of lactation?
  • NDC Co-lactation Feeding Plan (to be adapted)
  • Case report of preparation for induction of lactation in a cisgender woman (NDC Clinical Guidelines)
  • Research about induction of lactation in transgender patients
  • Acknowledgement of the pioneering contribution made by the Newman Goldfarb Protocols for Induction of Lactation - and why the NDC Clinical Guideline for Induction of Lactation has differences

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  • PBL Advanced
  • S14: Induction of lactation

Induction of lactation: taking a history and why each question matters

Dr Pamela Douglas22nd of Dec 202522nd of Dec 2025

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History Items that are important to ask about Why the answer matters
Age Patient's age Combined oral contraceptive pill (COCP) contraindicated over 35 years of age due to increased risks of side-effects (e.g.thrombosis)
Gender identity Female
Transgender Transgender woman who wishes to induce lactation should be managed in partnership with her endocrinologist
Previous pregnancies or birth experience Breastmilk production is likely to be higher if the woman has had a previous pregnancy, since pregnancy ‘primes’ the breast for lactation with hormones reaching much higher levels than achieved with a COCP, for instance
Who will/has birthed the infant? Surrogate mother
Infant is adopted
Partner
Other - please detail
Reason not able to/not choosing to conceive Medical condition - please detail May be relevant to considerations of risks of hormonal induction
Infertility without identifiable cause
Other - please detail
Past medical/surgical history Cigarette smoking - pack years, number of cigarettes daily COCP contraindicated if > 15 cigs/day. If less than 15/day and < 35 years of age, you may weigh up risks of cardiovascular disease (myocardial infarction, thrombosis, stroke in discussion with the patient.
Vaping
Thrombosis History of deep venous thrombosis, stroke, or clotting disorder is contraindication
Other cardiac condition - please detail Consider relvance to COCP and domperidone
Hypertension COCP may be contraindicated
Migraine COCP may be contraindicated
Diabetes Check lipid profile and blood pressure. COCP contraindicated if hypertriglyceridemia or hypertension
Cardiac arrhythmia Domperidone contraindicated
Liver disease COCP may be contraindicated
Renal or adrenal insufficiency Drosperinone (new generation progesterone in Yasmin) contraindicated
Depression Domperidone is self-reported to worsen mood in some women
Medications Taking drugs which interact with domperidone or prolong QTc interval? The most common examples are erythromycin, fluconazole, citalopram and escitalopram Domperidone is contraindicated when these other medications are being taken.
Previous COCP use - please detail Helps determine tolerance to and potential side-effects of COCP use
Allergies
Family history Sudden unexplained cardiac death Domperidone may be contraindicated
Cardiac arrhythmia Domperidone may be contraindicated
Clotting or bleeding disorders May be relevant to your patient's use of COCP

You can find this item downloadable as a pdf or word document for use in clinical consultations if you are participating in the NDC Lactation Fellowship.

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Next up in Induction of lactation

NDC Clinical Guidelines Induction of Lactation Part 1. The most reliable element in non-puerperal induction of lactation protocols is stimulation of the breasts and nipples + frequent flexible milk removal

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How should a patient prepare for pumping to induce lactation?

Your patient will find nipple and breast stimulation most efficient if they use a hospital grade double-flanged electric pump.

Some patients like to use a wearable pump too, for convenience. There are risks associated with a wearable pump though such as

  • Moisture associated skin damage

  • Poorer fit with increased risk of nipple pain or damage

  • Breast inflammation.

This is why I recommend a hand held hospital grade double pump as the most important item, and only careful intermittent use of the wearable pump.

The NDC guidelines part 3: manual stimulation and pumping for induction of lactation

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Possums acknowledges the traditional owners of the lands upon which The Possums Programs have been created, the Yuggera and Turrbal Peoples. We acknowledge that First Nations have breastfed, slept with, and lovingly raised their children on Australian lands for at least 65,000 years, to become the oldest continuous living culture on Earth. Possums stands with the Uluru Statement from the Heart.