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  • Insufficient breastmilk to exclusively meet an infant's caloric need: prevalence and aetiology
  • Comments on 'Causes of low supply + investigations' 9_6_25
  • Delayed secretory activation (often inaccurately referred to as delayed onset of lactation)
  • Insufficient glandular tissue and breast hypoplasia

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  • PBL Advanced
  • S5: Milk production: models, mechanisms, management, evolutionarily-aligned breastfeeding patterns
  • CH 4: Low supply: when breastmilk production is less than the infant's caloric needs in exclusive breastfeeding
  • PT 4.1: Aetiology + investigations

Comments on 'Causes of low supply + investigations' 9_6_25

Dr Pamela Douglas9th of Jun 20259th of Jun 2025

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Gestational anaemia does not impact upon breastfeeding outcomes

A 2025 study from the FinnBrain Birth Cohort (2011-2015) investigated women whose hameoglobin levels were available in the third trimester (n = 1088). Gestational anemia in the third trimester, defined as Hb < 110gm/l (n = 150), was not associated with duration or quality of breastfeeding.

Reference

Singh S, Van de Wouw M, Tomfohr-Madsen L. The role of green and blue spaces in perinatal maternal mental health outcomes during the transition to parenthood. Environment International. 2025;2025:109572.

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Delayed secretory activation (often inaccurately referred to as delayed onset of lactation)

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What is delayed secretory activation?

Delayed onset of lactation is a commonly used term, but is scientifically inaccurate, since lactation commences during pregnancy, with secretory differentiation. You can read about lactogenesis here. The more accurate term is delayed onset of secretory activation.

Delayed onset of secretory activation is independently associated with shorter breastfeeding duration. It is currently defined as the milk coming in later than 72 hours after delivery.

However, research has shown that secretory activation may occur up to five days postbirth in otherwise well women who go on to breastfeed successfully, and this tension between prevailing definitions and research findings need to be borne in mind by the clinician.

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Possums acknowledges the traditional owners of the lands upon which The Possums Programs have been created, the Yuggera and Turrbal Peoples. We acknowledge that First Nations have breastfed, slept with, and lovingly raised their children on Australian lands for at least 65,000 years, to become the oldest continuous living culture on Earth. Possums stands with the Uluru Statement from the Heart.